[“Let Inga Tell You,” La Jolla Light, published May 1, 2019] ©2019
I didn’t jump on the ancestry band wagon
right away since both my mother’s and father’s families kept good genealogical
records back many generations – even centuries. But I was definitely
curious about the carrier status, health predispositions, wellness predictions,
and traits data that was now available.
My sister, a year younger, decided against it. “I don’t want any bad
news,” she maintained.
“Not to put too fine a point on it,” I replied, “but we’re SEVENTY. How
much bad news could there be? We’ve already aged out of Early Onset Dementia!”
But she is unmoved.
23andme is careful to inform you that with each of the afflictions they
test your genes for, they are only testing for specific variants and just
because you don’t test positive for those variants doesn’t mean you’re home
free on this disease.
They emphasize that there are all manner of life style and “other
factors” that could contribute to your succumbing to these maladies besides
your DNA. Still, I confess it’s comforting to know that if I crump from one of
these, it’s my own fault and not my genes’.
I was especially happy to discover that the variants they tested for me
did not detect the variants for BRCA1/BCRA2 (breast cancer), Late-Onset
Alzheimers and Parkinsons.
I did, however, test positive for one of the two variants they tested
for Age-related Macular Degeneration. Apparently, it’s pretty common in people
of European descent.
I was genuinely pleased that “variant not detected” came up on all 44
Carrier traits they tested, even though I had no idea what most of them are. I
am not, for example, a carrier of the gene for Hereditary Fructose Intolerance,
MCAD Deficiency, Rhizomelic Chondrodysplasia Punctata Type 1, Usher Syndrome
Type 1F, or Dihydrolipoamide Dehydrogenase Deficiency. None of them sound like
a good time.
The actually fun parts of 23andme were in the Traits sections which
predicted whether you were or less likely to have certain qualities related to
appearance, weight, food preferences, sleep patterns, and general wellness.
23andme correctly predicted that I was “likely to have blue or green
eyes” (blue; I’m Northern European); “more likely than average to be afraid of heights”
(utterly deathly afraid of heights over three feet); “likely lighter skin”
(Northern European thing again); “less likely to be able to match a musical
pitch” (and then some: I’m totally tone deaf), “likely lactose tolerant” (yup);
“likely no unibrow” (correct, but seriously??); “less likely to get dandruff”
(true, but see “seriously??” above); “likely no cleft chin or dimples; and
“likely to experience hair photobleaching” (i.e. hair lightens after long
exposure to the sun). My hair always lightened multiple shades if I sat out in
the sun which I don’t any more after having malignant melanoma, an affliction,
by the way, that is not tested. Personally, I think it had everything to do
with all those youth baseball and soccer tournaments in the blazing sun rather
than genetics anyway.
But 23andme totally struck out on other traits: “likely a lot of
freckles” (nary a one); “less likely to have lots of baby hair at birth” (born
with a full head of hair); “less likely to have thick hair” (I STILL get my
hair thinned every three weeks or it’s like a mattress on my head); “slightly
higher odds of disliking cilantro” (I adore cilantro and consider it one of the
basic four food groups); “likely to have a muscle composition common in elite
power athletes” (I’m still laughing); and “likely to consume more caffeine”
(definitely not so since I inherited my mother’s severe sensitivity to caffeine).
23andme predicted I preferred “sweet over salty” which may technically
be true but I’ve never met a potato chip I didn’t like.
Where they really struck out was in the “Sleep and Wakeup Time”
category. According to them “based on your genetics, you’re likely to move about
an average amount during sleep” which they note would be about 12 times an
hour. As a sufferer of Restless Leg Syndrome (which sounds so innocuous but is
utterly brutal), I move about 12 times a minute. Interestingly, this can be a
hereditary ailment which I’m sincerely hoping for my younger son’s sake is
not. (My older son, noting the afflictions that have plagued his aging parents,
is increasingly grateful he’s adopted.)
Where 23andme struck out the most, however (besides the elite athletes
thing) is the prediction that I am “likely to wake up around 6:42 a.m.” As far
as I’m concerned, anything before 10 a.m. is still the night before. It
predicted that I am a morning person which I have never ever ever been in my
whole life.
Still, it’s been a fun exercise and there are always new reports coming
out. So far no really bad news and if some comes out, how hard is it to hit
“Delete”?